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Karyopharm Therapeutics (NASDAQ:KPTI) major shareholder Marcin Czernik unloaded 8,027 shares of Karyopharm Therapeutics stock on the open market in a transaction that occurred on Friday, August 15th. The stock was sold at an average price of $39.11, for a total transaction of $313,935.97. The sale was disclosed in a legal filing with the SEC, which is available at this link. Major shareholders that own at least 10% of a company’s shares are required to disclose their sales and purchases with the SEC.

Shares of Karyopharm Therapeutics (NASDAQ:KPTI) traded down 2.74% during mid-day trading on Wednesday, hitting $36.50. 89,316 shares of the company’s stock traded hands. Karyopharm Therapeutics has a 52-week low of $15.50 and a 52-week high of $47.98. The stock has a 50-day moving average of $36.98 and a 200-day moving average of $34.43. The company’s market cap is $1.192 billion.

Karyopharm Therapeutics (NASDAQ:KPTI) last issued its quarterly earnings data on Thursday, August 7th. The company reported ($1.02) EPS for the quarter, missing the Thomson Reuters consensus estimate of ($0.50) by $0.52. On average, analysts predict that Karyopharm Therapeutics will post $-2.19 earnings per share for the current fiscal year.

A number of research firms have recently commented on KPTI. Analysts at Leerink Swann cut their price target on shares of Karyopharm Therapeutics from $63.00 to $60.00 in a research note on Friday, August 8th. Analysts at Oppenheimer downgraded shares of Karyopharm Therapeutics from an “outperform” rating to a “market perform” rating in a research note on Monday, July 7th. One analyst has rated the stock with a hold rating and two have given a buy rating to the stock. The company presently has a consensus rating of “Buy” and an average price target of $52.67.

Karyopharm Therapeutics Inc is a clinical-stage pharmaceutical company focused on the discovery and development of drugs directed against nuclear transport targets for the treatment of cancer and other major diseases.

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