Repligen (NASDAQ: RGEN) and DARA Biosciences (NASDAQ:DARA) are both healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, profitabiliy, valuation, dividends, institutional ownership and earnings.

Institutional & Insider Ownership

94.4% of Repligen shares are owned by institutional investors. 2.3% of Repligen shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.


This table compares Repligen and DARA Biosciences’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Repligen 10.03% 7.12% 4.25%
DARA Biosciences -228.42% -145.61% -100.38%

Earnings & Valuation

This table compares Repligen and DARA Biosciences’ gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio EBITDA Earnings Per Share Price/Earnings Ratio
Repligen $110.04 million 12.15 $27.41 million $0.20 196.15
DARA Biosciences N/A N/A N/A N/A N/A

Repligen has higher revenue and earnings than DARA Biosciences.

Analyst Ratings

This is a summary of current recommendations for Repligen and DARA Biosciences, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Repligen 0 2 1 0 2.33
DARA Biosciences 0 0 0 0 N/A

Repligen currently has a consensus target price of $35.67, suggesting a potential downside of 9.08%. Given Repligen’s higher possible upside, research analysts clearly believe Repligen is more favorable than DARA Biosciences.


Repligen beats DARA Biosciences on 8 of the 8 factors compared between the two stocks.

About Repligen

Repligen Corporation is a bioprocessing company. The Company is focused on the development, manufacture and commercialization of products used to improve the interconnected phases of the biological drug manufacturing process. The Company’s portfolio includes protein products, chromatography products, and filtration products. It provides Protein A ligands, a component of Protein A chromatography resins (media) used in the purification of virtually all monoclonal antibody (mAb)-based drugs on the market or in development. Its chromatography portfolio includes various products used in the downstream purification and quality control of biological drugs. Its OPUS pre-packed chromatography columns (PPCs) are used in the purification of clinical-stage biologics. Its filtration products include XCell Alternating Tangential Flow (ATF) Systems and Sius tangential flow filtration (TFF) cassettes. Sius TFF cassettes are used to concentrate clinical and commercial-stage biologic drugs.

About DARA Biosciences

DARA BioSciences Inc is specialty pharmaceutical company based in the United States. The Company’s primary focus is on the commercialization of oncology treatment and oncology supportive care pharmaceutical products, including Soltamox, an oral solution of tamoxifen citrate; cancer support therapeutics, including Gelclair, indicated for the treatment of oral mucositis and Bionect, for the management of irritation of the skin as well as first and second degree burns, and Three Mission Pharmacal products, including Ferralet 90 (for anemia), Binosto (alendronate sodium effervescent tablet indicated for the treatment of osteoporosis) and Aquoral (for cancer related dry mouth). The Company has a clinical development asset, KRN5500, which is a Phase II product candidate targeted for treating cancer patients with painful treatment-refractory chronic chemotherapy induced peripheral neuropathy. The Company is a subsidiary of Midatech Pharma Plc.

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