Antares Pharma (NASDAQ: ATRS) and Alphatec Holdings (NASDAQ:ATEC) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, profitabiliy, institutional ownership, valuation, dividends, analyst recommendations and risk.


This table compares Antares Pharma and Alphatec Holdings’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Antares Pharma -41.26% -45.05% -30.66%
Alphatec Holdings -23.27% N/A -29.46%

Analyst Recommendations

This is a breakdown of recent ratings for Antares Pharma and Alphatec Holdings, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Antares Pharma 0 0 1 1 3.50
Alphatec Holdings 0 0 0 0 N/A

Antares Pharma currently has a consensus target price of $3.15, indicating a potential upside of 10.14%. Given Antares Pharma’s higher probable upside, analysts plainly believe Antares Pharma is more favorable than Alphatec Holdings.

Institutional and Insider Ownership

32.1% of Antares Pharma shares are owned by institutional investors. Comparatively, 21.4% of Alphatec Holdings shares are owned by institutional investors. 11.6% of Antares Pharma shares are owned by insiders. Comparatively, 23.6% of Alphatec Holdings shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Risk & Volatility

Antares Pharma has a beta of 0.67, suggesting that its share price is 33% less volatile than the S&P 500. Comparatively, Alphatec Holdings has a beta of 1.35, suggesting that its share price is 35% more volatile than the S&P 500.

Earnings and Valuation

This table compares Antares Pharma and Alphatec Holdings’ gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio EBITDA Earnings Per Share Price/Earnings Ratio
Antares Pharma $51.91 million 8.59 -$19.23 million ($0.14) -20.43
Alphatec Holdings N/A N/A N/A ($3.37) -0.58

Alphatec Holdings has higher revenue, but lower earnings than Antares Pharma. Antares Pharma is trading at a lower price-to-earnings ratio than Alphatec Holdings, indicating that it is currently the more affordable of the two stocks.


Antares Pharma beats Alphatec Holdings on 6 of the 11 factors compared between the two stocks.

About Antares Pharma

Antares Pharma, Inc. (Antares) is a specialty pharmaceutical company that focuses on developing and commercializing self-administered parenteral pharmaceutical products and technologies. The Company develops, manufactures and commercializes therapeutic products using its drug delivery systems. Its subcutaneous injection technology platforms include VIBEX disposable pressure-assisted auto injector system suitable for branded and generic injectable drugs in unit dose containers, reusable needle-free spring-action injector devices, and disposable multi-use pen injectors for use with cartridges. The Company makes a reusable, needle-free spring action injection device, ZOMA-Jet or Twin-Jector, which is marketed through its partners for use with human growth hormone (hGH). The Company operates through drug delivery segment, which includes self-administered parenteral pharmaceutical products and technologies.

About Alphatec Holdings

Alphatec Holdings, Inc. is a medical technology company. The Company through its subsidiary, Alphatec Spine, Inc. and its subsidiaries, designs, develops, manufactures and markets products for the surgical treatment of spine disorders. Its product portfolio and pipeline addresses the cervical, thoracolumbar and intervertebral regions of the spine and covers a range of spinal disorders and surgical procedures. Its products include Cervical and Cervico-Thoracic Products, which include Trestle Luxe Anterior Cervical Plate System and Pegasus Anchored Cervical Interbody; Thoracolumbar Fixation Products, which include Arsenal Degenerative System and OsseoScrew Spinal Fixation System; Spinal Spacers, which include Battalion Universal Spacer System and Alphatec Solus Locking ALIF Spinal Spacer; minimally invasive surgery Products, which include Illico Minimally Invasive Surgery System and BridgePoint Spinous Process Fixation System, and Biologics, which include Neocore Osteoconductive Matrix.

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