XOMA Corporation (NASDAQ: XOMA) and Soligenix (OTC:SNGX) are both small-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, valuation, institutional ownership, risk, profitability, earnings and analyst recommendations.

Analyst Ratings

This is a breakdown of recent recommendations for XOMA Corporation and Soligenix, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XOMA Corporation 0 2 2 0 2.50
Soligenix 0 0 2 0 3.00

XOMA Corporation presently has a consensus target price of $17.00, indicating a potential downside of 7.05%. Soligenix has a consensus target price of $8.00, indicating a potential upside of 250.88%. Given Soligenix’s stronger consensus rating and higher possible upside, analysts clearly believe Soligenix is more favorable than XOMA Corporation.

Earnings & Valuation

This table compares XOMA Corporation and Soligenix’s top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio EBITDA Earnings Per Share Price/Earnings Ratio
XOMA Corporation $12.31 million 11.29 -$30.55 million ($7.32) -2.50
Soligenix $9.15 million N/A -$5.45 million N/A N/A

Soligenix has higher revenue, but lower earnings than XOMA Corporation.

Institutional & Insider Ownership

32.9% of XOMA Corporation shares are held by institutional investors. 3.0% of XOMA Corporation shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Profitability

This table compares XOMA Corporation and Soligenix’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
XOMA Corporation -329.42% N/A -155.46%
Soligenix -233.27% -196.47% -122.14%

Summary

Soligenix beats XOMA Corporation on 5 of the 9 factors compared between the two stocks.

About XOMA Corporation

XOMA Corporation is a development-stage biotechnology company. The Company focuses on the discovery and development of monoclonal antibody-based therapeutics. It has five products in its endocrine portfolio, two of which are developed as part of its XOMA Metabolism (XMet) platform. Its products include XOMA 358, XOMA 129, XOMA 213 and Gevokizumab. Its XOMA 358 is meant for long-acting treatment of hyperinsulinemic hypoglycemia. XOMA 129 is meant for rapid onset, short-acting treatment of severe acute hypoglycemia. XOMA 213 is a Phase II-ready product candidate targeting the prolactin receptor, as well as research-stage programs targeting the parathyroid receptor (PTH1R) and the adrenal corticotropic hormone (ACTH). Gevokizumab is a humanized monoclonal antibody with allosteric properties that has the potential to treat patients with a range of inflammatory diseases. Its technologies include Antibody Discovery Advanced Platform Technologies (ADAPT), ModulX and OptimX.

About Soligenix

Soligenix, Inc. is a late-stage biopharmaceutical company. The Company is focused on developing and commercializing products to treat rare diseases. The Company operates through two segments: BioTherapeutics and Vaccines/BioDefense. Its BioTherapeutics segment is developing a photodynamic therapy (SGX301) utilizing topical synthetic hypericin activated with safe visible light for the treatment of cutaneous T-cell lymphoma (CTCL), formulations of oral beclomethasone 17,21-dipropionate (BDP) for the prevention/treatment of gastrointestinal (GI) disorders characterized by severe inflammation, and its innate defense regulator (IDR) technology, dusquetide (SGX942) for the treatment of oral mucositis in head and neck cancer. Its Vaccines/BioDefense business segment includes active development programs for RiVax, its ricin toxin vaccine candidate, OrbeShield, its GI acute radiation syndrome (GI ARS) therapeutic candidate, and SGX943, its melioidosis therapeutic candidate.

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