Alphatec Holdings (NASDAQ: ATEC) and Sequenom (NASDAQ:SQNM) are both medical companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, risk, profitability, earnings, valuation and dividends.

Earnings & Valuation

This table compares Alphatec Holdings and Sequenom’s top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio EBITDA Earnings Per Share Price/Earnings Ratio
Alphatec Holdings $106.16 million 0.31 -$2.79 million ($3.01) -1.00
Sequenom N/A N/A N/A ($0.34) -7.03

Sequenom has higher revenue, but lower earnings than Alphatec Holdings. Sequenom is trading at a lower price-to-earnings ratio than Alphatec Holdings, indicating that it is currently the more affordable of the two stocks.

Risk & Volatility

Alphatec Holdings has a beta of 1.27, meaning that its share price is 27% more volatile than the S&P 500. Comparatively, Sequenom has a beta of 1.17, meaning that its share price is 17% more volatile than the S&P 500.

Analyst Ratings

This is a summary of recent ratings and recommmendations for Alphatec Holdings and Sequenom, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alphatec Holdings 0 0 1 0 3.00
Sequenom 0 0 0 0 N/A

Alphatec Holdings presently has a consensus price target of $4.00, indicating a potential upside of 32.89%. Given Alphatec Holdings’ higher possible upside, analysts plainly believe Alphatec Holdings is more favorable than Sequenom.


This table compares Alphatec Holdings and Sequenom’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Alphatec Holdings -25.13% N/A -31.74%
Sequenom -21.54% N/A -25.05%

Insider and Institutional Ownership

20.6% of Alphatec Holdings shares are owned by institutional investors. Comparatively, 46.0% of Sequenom shares are owned by institutional investors. 34.9% of Alphatec Holdings shares are owned by company insiders. Comparatively, 3.1% of Sequenom shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.


Alphatec Holdings beats Sequenom on 5 of the 9 factors compared between the two stocks.

About Alphatec Holdings

Alphatec Holdings, Inc. is a medical technology company. The Company through its subsidiary, Alphatec Spine, Inc. and its subsidiaries, designs, develops, manufactures and markets products for the surgical treatment of spine disorders. Its product portfolio and pipeline addresses the cervical, thoracolumbar and intervertebral regions of the spine and covers a range of spinal disorders and surgical procedures. Its products include Cervical and Cervico-Thoracic Products, which include Trestle Luxe Anterior Cervical Plate System and Pegasus Anchored Cervical Interbody; Thoracolumbar Fixation Products, which include Arsenal Degenerative System and OsseoScrew Spinal Fixation System; Spinal Spacers, which include Battalion Universal Spacer System and Alphatec Solus Locking ALIF Spinal Spacer; minimally invasive surgery Products, which include Illico Minimally Invasive Surgery System and BridgePoint Spinous Process Fixation System, and Biologics, which include Neocore Osteoconductive Matrix.

About Sequenom

Sequenom, Inc. is a life sciences company. The Company serves patients and physicians by providing early patient management information. The Company operates through Sequenom Laboratories segment. It conducts its business as a molecular diagnostics clinical laboratory located in San Diego, California and Raleigh-Durham, North Carolina. Its testing focus is on prenatal health that includes molecular-based laboratory developed tests (LDTs). The Company’s diagnostic services are provided through its subsidiary, Sequenom Center for Molecular Medicine LLC (SCMM), doing business as Sequenom Laboratories. Sequenom Laboratories develops and validates its tests to be used as a testing service to physicians. Sequenom Laboratories is focused on developing and offering a menu of tests for prenatal continuum of care. The Sequenom Laboratories’ test offerings in the prenatal market include MaterniT21 PLUS LDT, HerediT CF test, SensiGene RhD test, VisibiliT test and Test Send-out Agreements.

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