AnaptysBio, Inc. (NASDAQ:ANAB) was downgraded by Zacks Investment Research from a “buy” rating to a “hold” rating in a report released on Wednesday.

According to Zacks, “AnaptysBio, Inc. is a biotechnology company. It involved in the discovery and development of therapeutic antibodies for inflammation and immuno-oncology primarily in the Unites states. AnaptysBio, Inc. is based in San Diego, California. “

A number of other research analysts have also recently commented on ANAB. Robert W. Baird initiated coverage on AnaptysBio in a research note on Monday, July 10th. They set an “outperform” rating and a $36.00 target price on the stock. Credit Suisse Group upped their target price on AnaptysBio from $34.00 to $38.00 and gave the company an “outperform” rating in a research note on Friday, August 25th. Stifel Nicolaus reaffirmed a “buy” rating and set a $35.00 target price on shares of AnaptysBio in a research note on Tuesday, September 12th. Royal Bank Of Canada initiated coverage on AnaptysBio in a research note on Thursday, September 14th. They set an “outperform” rating and a $40.00 target price on the stock. Finally, JMP Securities upped their target price on AnaptysBio from $45.00 to $82.00 and gave the company an “outperform” rating in a research note on Tuesday. One equities research analyst has rated the stock with a hold rating and six have assigned a buy rating to the company. The company presently has a consensus rating of “Buy” and a consensus target price of $59.14.

Shares of AnaptysBio (NASDAQ ANAB) traded down 0.67% during midday trading on Wednesday, hitting $69.94. The stock had a trading volume of 1,201,177 shares. AnaptysBio has a 52-week low of $15.17 and a 52-week high of $74.00. The company’s market cap is $1.42 billion. The company’s 50 day moving average is $35.88 and its 200 day moving average is $35.88.

AnaptysBio (NASDAQ:ANAB) last released its earnings results on Thursday, August 10th. The biotechnology company reported ($0.13) EPS for the quarter, beating analysts’ consensus estimates of ($0.42) by $0.29. The business had revenue of $7.00 million for the quarter, compared to the consensus estimate of $3.45 million. On average, analysts anticipate that AnaptysBio will post ($1.98) earnings per share for the current year.

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In related news, major shareholder Holdings A/S Novo sold 356,300 shares of the stock in a transaction that occurred on Monday, August 21st. The stock was sold at an average price of $21.10, for a total value of $7,517,930.00. Following the transaction, the insider now owns 1,936,604 shares of the company’s stock, valued at $40,862,344.40. The sale was disclosed in a legal filing with the SEC, which can be accessed through the SEC website. Also, major shareholder Ventures Vii L. P. Avalon sold 37,040 shares of the stock in a transaction that occurred on Wednesday, July 26th. The stock was sold at an average price of $24.35, for a total value of $901,924.00. The disclosure for this sale can be found here. In the last ninety days, insiders have sold 1,133,940 shares of company stock worth $24,223,316.

A number of large investors have recently made changes to their positions in the stock. Perceptive Advisors LLC bought a new position in AnaptysBio in the first quarter worth approximately $24,474,000. Artal Group S.A. grew its stake in AnaptysBio by 459.4% in the second quarter. Artal Group S.A. now owns 250,000 shares of the biotechnology company’s stock worth $5,983,000 after purchasing an additional 205,310 shares in the last quarter. Marshall Wace North America L.P. bought a new position in AnaptysBio in the first quarter worth approximately $6,924,000. MARSHALL WACE ASIA Ltd bought a new position in AnaptysBio in the first quarter worth approximately $6,924,000. Finally, Vanguard Group Inc. grew its stake in AnaptysBio by 22.6% in the second quarter. Vanguard Group Inc. now owns 206,031 shares of the biotechnology company’s stock worth $4,931,000 after purchasing an additional 37,932 shares in the last quarter. 71.35% of the stock is currently owned by institutional investors.

AnaptysBio Company Profile

AnaptysBio, Inc is a United States-based biotechnology company. The Company is engaged in developing antibody product candidates focused on unmet medical needs in inflammation and immuno-oncology. The Company develops its product candidates using its antibody discovery technology platform, which is designed to replicate, in vitro, the natural process of antibody generation.

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