Protagonist Therapeutics (NASDAQ: PTGX) is one of 198 publicly-traded companies in the “Biotechnology & Medical Research” industry, but how does it weigh in compared to its peers? We will compare Protagonist Therapeutics to similar companies based on the strength of its valuation, earnings, risk, dividends, analyst recommendations, institutional ownership and profitability.

Valuation & Earnings

This table compares Protagonist Therapeutics and its peers top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue EBITDA Price/Earnings Ratio
Protagonist Therapeutics N/A -$47.60 million -4.87
Protagonist Therapeutics Competitors $207.78 million -$2.31 million 0.68

Protagonist Therapeutics’ peers have higher revenue and earnings than Protagonist Therapeutics. Protagonist Therapeutics is trading at a lower price-to-earnings ratio than its peers, indicating that it is currently more affordable than other companies in its industry.

Institutional & Insider Ownership

48.0% of Protagonist Therapeutics shares are owned by institutional investors. Comparatively, 46.7% of shares of all “Biotechnology & Medical Research” companies are owned by institutional investors. 13.8% of shares of all “Biotechnology & Medical Research” companies are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Analyst Ratings

This is a breakdown of recent ratings and target prices for Protagonist Therapeutics and its peers, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics 0 0 2 0 3.00
Protagonist Therapeutics Competitors 476 2259 6167 119 2.66

Protagonist Therapeutics currently has a consensus price target of $38.00, indicating a potential upside of 138.54%. As a group, “Biotechnology & Medical Research” companies have a potential upside of 13.27%. Given Protagonist Therapeutics’ stronger consensus rating and higher possible upside, equities analysts plainly believe Protagonist Therapeutics is more favorable than its peers.

Risk & Volatility

Protagonist Therapeutics has a beta of -2.55, meaning that its share price is 355% less volatile than the S&P 500. Comparatively, Protagonist Therapeutics’ peers have a beta of 1.63, meaning that their average share price is 63% more volatile than the S&P 500.


This table compares Protagonist Therapeutics and its peers’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Protagonist Therapeutics N/A -59.45% -54.53%
Protagonist Therapeutics Competitors -3,965.85% -118.54% -43.71%

About Protagonist Therapeutics

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company with a peptide technology platform focused on discovering and developing new chemical entities (NECs) to address significant unmet medical needs. The Company’s product pipeline includes PTG-100, PTG-200 and PTG-300. Its primary focus is on developing oral peptide drugs that target biological pathways also targeted by marketed injectable antibody drugs. PTG-100 is an oral, alpha-4-beta-7 (a4b7) integrin-specific antagonist peptide product candidate, which has completed a Phase I clinical trial in normal healthy volunteers (NHVs). PTG-100 is being developed for treatment of moderate-to-severe ulcerative colitis (UC). PTG-200 is an oral Interleukin-23 receptor (IL-23R) antagonist being developed for moderate-to-severe Crohn’s disease (CD). PTG-200 is in investigational new drug (IND) enabling studies. PTG-300 is an injectable hepcidin mimetic for treatment of iron overload related rare diseases.

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