Tonix Pharmaceuticals Holding Corp. (NASDAQ: TNXP) and Echo Therapeutics (OTCMKTS:ECTE) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their dividends, earnings, institutional ownership, analyst recommendations, risk, valuation and profitability.

Risk & Volatility

Tonix Pharmaceuticals Holding Corp. has a beta of 2.9, meaning that its stock price is 190% more volatile than the S&P 500. Comparatively, Echo Therapeutics has a beta of 1.68, meaning that its stock price is 68% more volatile than the S&P 500.

Earnings & Valuation

This table compares Tonix Pharmaceuticals Holding Corp. and Echo Therapeutics’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio NetIncome Earnings Per Share Price/Earnings Ratio
Tonix Pharmaceuticals Holding Corp. N/A N/A -$38.84 million ($4.77) -0.75
Echo Therapeutics $60,000.00 8.00 -$22.19 million ($1.28) -0.03

Echo Therapeutics has higher revenue and earnings than Tonix Pharmaceuticals Holding Corp.. Tonix Pharmaceuticals Holding Corp. is trading at a lower price-to-earnings ratio than Echo Therapeutics, indicating that it is currently the more affordable of the two stocks.

Profitability

This table compares Tonix Pharmaceuticals Holding Corp. and Echo Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Tonix Pharmaceuticals Holding Corp. N/A -78.25% -73.14%
Echo Therapeutics N/A N/A 216.11%

Analyst Ratings

This is a summary of recent ratings and recommmendations for Tonix Pharmaceuticals Holding Corp. and Echo Therapeutics, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tonix Pharmaceuticals Holding Corp. 0 1 4 0 2.80
Echo Therapeutics 0 0 0 0 N/A

Tonix Pharmaceuticals Holding Corp. currently has a consensus price target of $8.33, indicating a potential upside of 132.13%. Given Tonix Pharmaceuticals Holding Corp.’s higher possible upside, equities research analysts clearly believe Tonix Pharmaceuticals Holding Corp. is more favorable than Echo Therapeutics.

Insider & Institutional Ownership

22.5% of Tonix Pharmaceuticals Holding Corp. shares are owned by institutional investors. 4.0% of Tonix Pharmaceuticals Holding Corp. shares are owned by insiders. Comparatively, 7.0% of Echo Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Summary

Echo Therapeutics beats Tonix Pharmaceuticals Holding Corp. on 6 of the 10 factors compared between the two stocks.

About Tonix Pharmaceuticals Holding Corp.

Tonix Pharmaceuticals Holding Corp., a clinical-stage pharmaceutical company, engages in developing pharmaceutical products for central nervous system disorders. The company’s lead program focuses on post-traumatic stress disorder (PTSD) that is characterized by chronic disability, inadequate treatment options, high utilization of healthcare services, and economic burden. Its lead product candidate includes TNX-102 SL, a cyclobenzaprine HCl sublingual tablet, which is in Phase III clinical stage for the treatment of PTSD; and Phase III clinical stage for the treatment of military-related PTSD. The company’s product candidates also include TNX-601, an oral formulation of tianeptine oxalate for PTSD and cognitive dysfunction associated with steroid use; TNX-801, a smallpox-preventing vaccine based on a live synthetic version of horsepox virus; TNX-301, a fixed-dose combination drug product for alcohol use disorders; and TNX-701 for radiation injuries. Tonix Pharmaceuticals Holding Corp. was founded in 2007 and is based in New York, New York.

About Echo Therapeutics

Echo Therapeutics, Inc. is a medical device company. The Company is engaged in developing a non-invasive, wireless continuous glucose monitoring (CGM) system with use in the wearable-health consumer market, diabetes outpatient market and in the hospital setting. The Company operates through the development of transdermal skin permeation and diagnostic medical devices segment. The Company has also developed its needle-free skin preparation device as a platform technology that allows for enhanced skin permeation enabling extraction of analytes, such as glucose, enhanced delivery of topical pharmaceuticals and other applications. The CGM System includes a skin preparation device, transdermal glucose sensor, battery and wireless transmitter. The Company has conducted several human feasibility clinical studies with its CGM System in healthy subjects, diabetics and critically ill patients, as well as a clinical study at several hospitals in the United States.

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