Cynapsus Therapeutics (CYNA) & XBiotech (XBIT) Head-To-Head Comparison

Cynapsus Therapeutics (NASDAQ: CYNA) and XBiotech (NASDAQ:XBIT) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, dividends, earnings, profitability, analyst recommendations, institutional ownership and valuation.

Analyst Recommendations

This is a breakdown of current ratings and recommmendations for Cynapsus Therapeutics and XBiotech, as provided by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cynapsus Therapeutics 0 0 0 0 N/A
XBiotech 0 1 1 0 2.50

XBiotech has a consensus target price of $13.00, indicating a potential upside of 217.07%. Given XBiotech’s higher probable upside, analysts plainly believe XBiotech is more favorable than Cynapsus Therapeutics.

Insider and Institutional Ownership

56.6% of Cynapsus Therapeutics shares are held by institutional investors. Comparatively, 11.0% of XBiotech shares are held by institutional investors. 35.7% of XBiotech shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.


This table compares Cynapsus Therapeutics and XBiotech’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Cynapsus Therapeutics N/A -35.81% -32.75%
XBiotech N/A -60.07% -55.80%

Earnings & Valuation

This table compares Cynapsus Therapeutics and XBiotech’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Cynapsus Therapeutics N/A N/A N/A $1.86 21.76
XBiotech N/A N/A -$52.76 million ($1.26) -3.25

XBiotech is trading at a lower price-to-earnings ratio than Cynapsus Therapeutics, indicating that it is currently the more affordable of the two stocks.


Cynapsus Therapeutics beats XBiotech on 5 of the 8 factors compared between the two stocks.

About Cynapsus Therapeutics

Cynapsus Therapeutics Inc is a Canada-based specialty central nervous system (CNS) pharmaceutical company. It develops a sublingual thin film for the potential treatment for on-demand management of debilitating OFF episodes associated with Parkinson’s disease (PD). The Company completed a Phase two clinical trial for its product candidate, APL-130277, a sublingual formulation of apomorphine hydrochloride, or apomorphine. Apomorphine is the only molecule approved for acute, intermittent treatment of OFF episodes for advanced PD patients, but is currently only approved as a subcutaneous injection in the United States. APL-130277 is a turning ON medication designed to convert a PD patient from the OFF to the ON state while avoiding the issues associated with subcutaneous delivery of apomorphine. It is designed to convert all types of OFF episodes, including morning OFF episodes. Furthermore, the Company has initiated its pivotal Phase three clinical program for APL-130277.

About XBiotech

XBiotech Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in discovering and developing True Human monoclonal antibodies for treating a range of different diseases. It focuses on its lead product candidate, Xilonix (MABp1), which is derived from a natural human immune response. The Company has also developed a True Human monoclonal antibody discovery platform and manufacturing system. Xilonix is a therapeutic antibody, which specifically neutralizes interleukin-1 alpha (IL-1a). Its pipeline includes various human antibodies for treating diseases, such as cancer, vascular disease, inflammatory skin disease and diabetes. The Company has completed a Phase III study in Europe for the treatment of symptomatic colorectal cancer. It also investigated its lead product candidate in clinical trials for other inflammatory conditions, including vascular disease, type II diabetes, acne, psoriasis, pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS).

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