Comparing Syndax Pharmaceuticals (SNDX) & Strongbridge Biopharma (SBBP)

Syndax Pharmaceuticals (NASDAQ: SNDX) and Strongbridge Biopharma (NASDAQ:SBBP) are both small-cap medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, profitability, dividends, earnings, analyst recommendations, valuation and risk.

Analyst Recommendations

This is a summary of recent recommendations for Syndax Pharmaceuticals and Strongbridge Biopharma, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Syndax Pharmaceuticals 0 0 8 0 3.00
Strongbridge Biopharma 0 0 3 0 3.00

Syndax Pharmaceuticals presently has a consensus target price of $26.43, indicating a potential upside of 159.87%. Strongbridge Biopharma has a consensus target price of $14.67, indicating a potential upside of 71.54%. Given Syndax Pharmaceuticals’ higher possible upside, research analysts clearly believe Syndax Pharmaceuticals is more favorable than Strongbridge Biopharma.

Institutional and Insider Ownership

61.7% of Syndax Pharmaceuticals shares are held by institutional investors. Comparatively, 64.0% of Strongbridge Biopharma shares are held by institutional investors. 24.1% of Syndax Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Profitability

This table compares Syndax Pharmaceuticals and Strongbridge Biopharma’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Syndax Pharmaceuticals -4,304.34% -57.90% -45.09%
Strongbridge Biopharma N/A -181.90% -38.62%

Earnings & Valuation

This table compares Syndax Pharmaceuticals and Strongbridge Biopharma’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Syndax Pharmaceuticals $1.22 million 203.32 -$44.47 million ($2.68) -3.79
Strongbridge Biopharma N/A N/A -$48.59 million ($3.38) -2.53

Syndax Pharmaceuticals has higher revenue and earnings than Strongbridge Biopharma. Syndax Pharmaceuticals is trading at a lower price-to-earnings ratio than Strongbridge Biopharma, indicating that it is currently the more affordable of the two stocks.

Summary

Syndax Pharmaceuticals beats Strongbridge Biopharma on 7 of the 11 factors compared between the two stocks.

About Syndax Pharmaceuticals

Syndax Pharmaceuticals, Inc (Syndax) is a clinical stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. The Company’s product candidate, entinostat, which was granted Breakthrough Therapy designation by the FDA following positive results from its Phase IIb clinical trial, ENCORE 301, is being evaluated in a Phase III clinical trial for advanced hormone receptor positive breast cancer. It is developing entinostat, which has direct effects on both cancer cells and immune regulatory cells, and SNDX-6352, an anti-CSF-1R monoclonal antibody, to enhance the body’s immune response on tumors that have shown sensitivity to immunotherapy. Entinostat is being evaluated as a combination therapeutic in Phase Ib/II clinical trials with Merck & Co., Inc. for non-small cell lung cancer and melanoma, with Genentech, Inc. for TNBC, and with Pfizer Inc. and Merck KGaA, Darmstadt, Germany, for ovarian cancer.

About Strongbridge Biopharma

Strongbridge Biopharma plc is a global commercial-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies for a range of diseases. The Company’s commercial product, KEVEYIS (dichlorphenamide), is indicated for the treatment of hyperkalemic, hypokalemic and related variants of primary periodic paralysis. The United States Food and Drug Administration (FDA) has granted orphan drug designation for KEVEYIS. The Company has a clinical-stage pipeline of therapies for endocrine diseases. The Company’s lead compounds include COR-003 (levoketoconazole), a cortisol synthesis inhibitor, and COR-005 (veldoreotide), a somatostatin analog (SSA). The Company is studying COR-003 for the treatment of endogenous Cushing’s syndrome. It is investigating COR-005 for the treatment of acromegaly. Both COR-003 and COR-005 have received orphan designation from the FDA and the European Medicines Agency (EMA).

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