Cytosorbents (CTSO) vs. Nanosphere (NSPH) Financial Analysis

Cytosorbents (NASDAQ: CTSO) and Nanosphere (NASDAQ:NSPH) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, dividends, valuation, risk, profitability, earnings and analyst recommendations.


This table compares Cytosorbents and Nanosphere’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Cytosorbents -67.83% -233.72% -57.58%
Nanosphere -99.68% -232.37% -65.52%

Analyst Recommendations

This is a breakdown of current ratings for Cytosorbents and Nanosphere, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cytosorbents 0 0 5 0 3.00
Nanosphere 0 0 0 0 N/A

Cytosorbents currently has a consensus target price of $10.65, indicating a potential upside of 52.14%.

Institutional and Insider Ownership

9.5% of Cytosorbents shares are owned by institutional investors. 5.6% of Cytosorbents shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Valuation & Earnings

This table compares Cytosorbents and Nanosphere’s gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Cytosorbents $9.53 million 21.07 -$11.93 million ($0.32) -21.88
Nanosphere N/A N/A N/A ($5.39) N/A

Nanosphere has lower revenue, but higher earnings than Cytosorbents. Cytosorbents is trading at a lower price-to-earnings ratio than Nanosphere, indicating that it is currently the more affordable of the two stocks.


Cytosorbents beats Nanosphere on 7 of the 9 factors compared between the two stocks.

Cytosorbents Company Profile

CytoSorbents Corporation is a critical care focused immunotherapy company. The Company is engaged in commercializing its product, CytoSorb, which is a blood purification technology with focus in preventing or treating multiple organ failure. The Company’s purification technologies are based on biocompatible, porous polymer beads that remove toxic substances from blood and other bodily fluids by pore capture and surface adsorption. The Company’s CytoSorb is an extracorporeal cytokine filter and is designed to reduce the cytokine storm that causes inflammation, organ failure and death in common critical illnesses, such as sepsis, burn injury, trauma, lung injury and pancreatitis. In addition, CytoSorb is used in other inflammatory conditions, such as cardiac surgery and autoimmune disease flares and cancer cachexia. It also has other products under development based upon its blood purification technology, including HemoDefend, ContrastSorb, DrugSorb, BetaSorb and others.

Nanosphere Company Profile

Nanosphere, Inc. is engaged in developing, manufacturing and marketing an advanced molecular diagnostics platform, the Verigene System, which enables genomic and protein testing on a single platform. The Verigene System includes a molecular diagnostics workstation that is a single use consumable for testing. The Verigene System consists of a microfluidics processor, a touchscreen reader and disposable test cartridges. The Company is focused on the infectious disease diagnostics market. Its Infectious Disease Assays include Respiratory Virus with Sub-Typing (RV+); Respiratory Pathogens/Expanded Panel (RP Flex); Bloodstream Infection (BSI) Panels, which include Blood Culture – Gram Positive (BC-GP), Blood Culture – Gram Negative (BC-GN) and Blood Culture – Yeast (BC-Y); C. difficile (CDF), and Enteric Panel (EP). Its Human Pharmacogenetic Assays include Hypercoagulation (FV, FII, MTHFR Panel) and CYP2C19 Genetic Variance. It is focused on the infectious disease diagnostics market.

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